Targeting the Microbiome: Therapeutic Approaches in Gastrointestinal Diseases

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Event Date
When

Friday, October 7, 2022
(7:45 AM CET – 4:35 PM CET)

Event Details

Experience in-person presentations by our expert presenters and join interactive working sessions.

Alimentiv Presents the 4th Annual Symposium on:
Targeting the Microbiome: Therapeutic Approaches in Gastrointestinal Diseases

Event Overview
This full-day, educational event is organized for and by members of the ATRC to understand the role of the microbiome and microbiome therapeutics in GI diseases such as IBD and NASH. The Symposium will bring together key stakeholders including gastroenterologists, basic & translational scientists, clinical pharmacologists, trialists and industry sponsors.

Location: Courtyard by Marriott Vienna Prater/Messe
Address: Trabrennstraße 4 Wien, 1020 Österreich
Website: courtyard-wien-messe.com
Symposium: 7:45 AM CET – 4:35 PM CET; Krieau 1 and 2.
Reception: 4:35 AM CET- 6:35 PM CET; Foyer, Ground Floor.

Expert Panel

Eugene Chang<br>MD
Eugene Chang
MD
University of Chicago, USA

Purna Kashyap<br>MBBS
Purna Kashyap
MBBS
Mayo Clinic, USA

Wouter de Jonge<br>PhD
Wouter de Jonge
PhD
Amsterdam UMC, The Netherlands

Jessica Allegretti<br>MD, MPH, FACG
Jessica Allegretti
MD, MPH, FACG
Harvard Medical School, USA

Christopher Ford<br>PhD
Christopher Ford
PhD
SERES Therapeutics, USA

Bernd Schnabl<br>MD
Bernd Schnabl
MD
University of California San Diego, USA

Amanda Prince<br>PhD
Amanda Prince
PhD
Vedanta Biosciences, USA

Vipul Jairath<br>MBChB, PhD, MRCP, FRCPC
Vipul Jairath
MBChB, PhD, MRCP, FRCPC
University of Western Ontario & Alimentiv, Canada

Harry Sokol<br>MD, PhD
Harry Sokol
MD, PhD
Sorbonne University and APHP, France

Agenda

7:45 AM CET Registration & Continental Breakfast
8:15 AM CET Welcome & Introductions
Niels Vande Casteele
— UCSD and AcelaBio, USA
Session 1: Host-Microbe Interactions in Health and Gastrointestinal Diseases
Chair: Niels Vande Casteele - UCSD and AcelaBio, USA
8:30 AM Keynote: Host-Microbe Interactions in Health and Gastrointestinal Diseases
Eugene Chang
— University of Chicago, USA
9:10 AM Keynote: Microbiome-Based Precision Medicine
Purna Kashyap
— Mayo Clinic, USA
9:50 AM Panel Discussion
10:05 AM Break
Session 2: Modulating Microbial Pathways as a Theraputic Intervention
Chair: João Sabino - KU Leuven, Belgium
10:20 AM Microbiota Guided Assessment of Therapy Response to Biologicals in IBD
Wouter de Jonge
— Amsterdam UMC, The Netherlands
10:40 AM The Evolution of the use of Faecal Microbiota Transplantation and Emerging Therapeutic Indications
Jessica Allegretti
— Harvard Medical School, USA
11:00 AM Leveraging Interventional Studies to Drive Novel Microbiome Therapeutic Development
Christopher Ford
— SERES Therapeutics, USA
11:20 AM Bacteriophages and Their Potential for Treatment of Gastrointestinal Diseases
Bernd Schnabl
— University of California San Diego, USA
11:40 AM Bench to Trial: Microbial-Immune Modulation in IBD with Defined Bacterial Consortia
Amanda Prince
— Vedanta Biosciences, USA
12:00 PM Panel Discussion
12:30 PM Lunch
Session 3: Microbiome Clinical Trial Design
Chair: Vipul Jairath - UWO and Alimentiv, Canada
1:30 PM Challenges in the Design and Conduct of Clinical Trials in Mild to Moderate Ulcerative Colitis
Vipul Jairath
— University of Western Ontario and Alimentiv, Canada
1:55 PM Considerations for Targeting the Microbiome in Clinical Development
Harry Sokol
— Sorbonne University and APHP, France
2:20 PM Panel discussion
2:40 PM Break
Session 4: Breakout Session
Chair: Niels Vande Casteele - UCSD and AcelaBio, USA
2:55 PM Instructions for Breakout Groups
3:00 PM Working groups to identify gaps and practicalities of implementation of microbiome studies in clinical trials
3:40 PM Working group presentation & general discussion
4:25 PM Summary of proposed objectives
4:35 PM Adjourn & Reception

Organizing Committee

Scientific Advisors